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116) Ehsan Hamzehpoor, Pegah Ghamari, Yuze Tao, Muhammad Ghufran Rafique, Zhenzhe Zhang, Mahdi Salehi, Robin S. Stein, Jorge Ramos-Sanchez, Arnaud W. Laramée, Gonzalo Cosa, Christian Pellerin, Ali Seifitokaldani, Rustam Z. Khaliullin, Dmytro F. Perepichka. Azatriangulene-Based Conductive C═C Linked Covalent Organic Frameworks with Near-Infrared Emission. Adv. Mater. 2024 https://doi.org/10.1002/adma.202413629

115) Patricia Islas, Casey M. Platnich, Yasser Gidi, Ryan Karimi, Lorianne Ginot, Daniel Saliba, Xin Luo, Gonzalo Cosa, Hanadi F. Sleiman. Automated Synthesis of DNA Nanostructures. Adv. Mater. 2024 https://doi.org/10.1002/adma.202403477

114) Michael D. Dore, Muhammad Ghufran Rafique, Tianxiao Peter Yang, Marlo Zorman, Casey M. Platnich, Pengfei Xu, Tuan Trinh, Felix J. Rizzuto, Gonzalo Cosa, Jianing Li, Alba Guarné & Hanadi F. Sleiman. Heat-activated growth of metastable and length-defined DNA fibers expands traditional polymer assembly. Nat. Commun. 2024, 15, 4384

113) Antonius T. M. Van Kessel and Gonzalo Cosa. Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis Proc. Nat. Acad. Sci. USA. 2024, 121, 21 e2317616121

112) McCain, J.; Martinez, S.R.; Fungo, F.; Sakaya, S.; Cosa, G. Two-Pronged Dormant Photosensitizer-Antibiotic Bacterial Inactivation: Mechanism, Dosage, and Cellular Evolution Visualized at the Single-Cell Level. J. Am. Chem. Soc. 2023, 145, 51, 28124-28136

111) Gidi, Y.; Ramos-Sanchez, J.; Lovell, T.C.; Glembockyte, V.; Cheah, I.K.; Schnermann, M.; Halliwell, B.; Cosa, G. Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids. J. Am. Chem. Soc. 2023, 145, 36, 19571-19577

110) Luo, X.; Saliba, D.; Yang, T.; Gentile, S.; Mori, K.; Islas Garcia, P.; Das, T.; Bagheri, N.; Porchetta, A.; Guarne, A.; Cosa, G.; Sleiman, H.F. Minimalist Design of Wireframe DNA Nanotubes: Tunable Geometry, Size, Chirality, and Dynamics. Angew. Chem. Int. Ed. 2023, 62, e202309869.

109) Gidi, Y.; Robert, A.; Tordo, A.; Lovell, T.C.; Ramos-Sanchez, J.; Sakaya, A.; Matthias, G.; Cosa, G. Binding and Sliding Dynamics of the Hepatitis C Virus Polymerase: Hunting the 3′ Terminus. ACS Infect. Dis. 2023, 9,8, 1488-1490.

108) Sosa, M.J.; Fonseca, J.L.; Sakaya, A.; Urrutia, M.N.; Petroselli, G.; Erra-Balsells, R.; Quindt, M.I.; Bonesi, S.M.; Cosa, G.; Vignoni, M.; Thomas, A.H. Alkylation converts riboflavin into an efficient photosensitizer of phospholipid membranes. Biochim. Biophys. Acta Biomembr. 2023, 1865 (5), 184155

107) Castillo-Pazos, D.J.; Lasso, J.D.; Hamzehpoor, E.; Ramos-Sanchez, J.; Salgado, J.M.; Cosa, G.; Perepichka, D.F.; Li, C.J. Triarylamines as catalytic donors in light-mediated electron donor–acceptor complexes. Chem. Sci. 2023, 14, 3470-3481.

106) Sakaya, A.; Bacellar, I.O.L.; Fonseca, J.L.; Durantini, A.; McCain, J.; Xu, L.; Vignoni, M.; Thomas, A.H.; Baptista, M.; Cosa, G. Singlet oxygen flux, associated lipid phooxidation, and membrane expansion dynamics visualized on giant unilamellar vesicles. Langmuir. 2023, 39, 1, 442-452.

105) Van Kessel, A.T.M.; Karimi, R.; Cosa, G. Live-cell imaging reveals impaired detoxification of a lipid-derived electrophiles is a hallmark of ferropotosis. Chem. Sci. 2022, 13, 9727-9738.

104) Naguib, M.; Feldman, N.; Zarodkiewicz, P.; Shropshire, H.; Biamis, C.; El-Halfawy, O.; McCain, J.; Dezanet, C.; Décout, J.; Chen, Y.; Cosa, G.; Valvano, M. An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria. PLoS Biol. 2022, 20 (5).

103) Sakaya, A.; Durantini, A.M.; Gidi, Y.; Šverko, T.; Wieczny, V.; McCain, J.; Cosa, C. Fluorescence-Amplified Detection of Redox Turnovers in Supported Lipid Bilayers Illuminates Redox Processes of α-Tocopherol. ACS Applied Materials & Interfaces. 2022, 14, 11, 13872-13882.

102) Lincoln, R.; Zhang, W.; Lovell, T.C.; Jodko-Piórecka, K.; Devlaminck, P.A.; Sakaya, A.; Van Kessel, A.; Cosa, G. Chemically Tuned, Reversible Fluorogenic Electrophile for Live Cell Nanoscopy. ACS Sensors. 2022, 7, 1, 166-174.

101) Hamzepoor, E.; Ruchlin, C.; Tao, Y.; Ramos-Sanchez J.E.; Titi, H.M.; Cosa, G.; Perepichka, D.F. Room temperature phosphorescence vs triplet−triplet annihilation in N substituted acridone solids. J. Phys. Chem. Lett. 2021, 12, 27, 6431-6438.

100) Rizzuto, F.; Platnich, C.M.; Luo, X.; Dore, M.L.; Lachance-Brais, C.; Cosa G.; Sleiman, H.F. A dissipative pathway for the structural evolution of DNA fibers. Nature Chem. 2021, 13, 843-849.

99) Dore, M.D.; Trinh, T.; Zorman, M.; de Rochambeau, D.; Platnich, C.M.; Xu, P.; Luo, X.; Remington, J.; Toader, V.; Cosa, G.; Li, J.; Sleiman, H.F. Thermosetting supramolecular polymerization of compartmentalized DNA fibers with stereo-sequence and length control. Chem. 2021, 7, 9, 2395-2414.

98) Lincoln, R.; Foret, M.K.; Do Carmo, S.; Cuello, A.; Cosa, G. FOCUS REVIEW - Connecting The ‘Dots’: From Free Radical Lipid Oxidation to Cell Pathology and Disease. Chem. Rev. 2020, 120, 12757-12787.

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97) Martinez, S.R.; Durantini, A.M.; Becerra, M.C.; Cosa, G. Real-Time Single-Cell Imaging Reveals Accelerating Lipid Peroxyl Radical Formation in Escherichia coli Triggered by a Fluoroquinolone Antibiotic. ACS Infect. Dis. 2020, 6, 2468-2477.

96) Gidi, Y.; Payne, L.; Glembockyte, V.; Michie, M.; Schnermann M, Cosa G. Unifying mechanism for thiol induced photoswitching and photostability of cyanine dyes. J. Am. Chem. Soc. 2020, 142, 12681-12689.

95) Platnich, C.; Rizutto, F.; Cosa, G.; Sleiman, H.F. Single-molecule methods in structural DNA nanotechnology. Chem. Soc. Rev. 2020, 49, 4220-4233.

94) Isselstein, M.; Zhang, L.; Glembockyte, V.; Brix, O.; Cosa, G.; Tinnefeld, P.; Cordes, T. Self-Healing Dyes – Keeping the Promise? J. Phys. Chem. Lett. 2020, 11, 4462-4480.

93) Dastpeyman, S.; Godin, R.; Cosa, G.; English, A. Quantifying Heme-Protein Maturation from Ratiometric Fluorescence Lifetime Measurements on the Single Fluorophore in Its GFP Fusion. J. Phys. Chem. A. 2020, 124, 746-754.

92) Platnich, C.; Hariri, A.; Sleiman, H.; Cosa, G. Advancing Wireframe DNA Nanostructures Using Single-Molecule Fluorescence Microscopy Techniques. Acc. Chem. Res. 2019, 52, 3199-3210.

91) Ablenas, C.; Gidi, Y.; Powdrill, M.; Ahmed, N.; Shaw, T.; Mesko, M.; Götte, M.; Cosa, G.; Pezacki, J. Hepatitis C virus helicase binding and activity monitored through site-specific labeling using an expanded genetic code. ACS Infect. Dis. 2019, 5, 2118-2126.

90) Sehayek, S.; Gidi, Y.; Glembockyte, V.; Brandão, H.; François, P.; Cosa, G.; Wiseman, P. A High-Throughput Image Correlation Method for Rapid Analysis of Fluorophore Photoblinking and Photobleaching Rates. ACS Nano. 2019, 13, 11955-11966.

89) Lincoln, R.; Van Kessel A.T.M.; Zhang, W.; Cosa, G. A Dormant BODIPY-Acrolein Singlet Oxygen Photosensitizer Intracellularly Activated upon Adduct Formation with Cysteine Residues. Photochem. Photobiol. Sci. 2019, 18, 2003-2011.

88) Greene, L. E.; Lincoln, R.; Cosa, G. Tuning Photoinduced Electron Transfer Efficiency of Fluorogenic BODIPY‐α‐Tocopherol Analogues. Photochem. Photobiol. 2019, 95, 192-201.

87) Foret, M. K.; Do Carmo, S.; Lincoln, R.; Greene, L. E.; Zhang, W.; Cuello, A. C.; Cosa, G. Effect of Antioxidant Supplements on Lipid Peroxidation Leves in Primary Cortical Neuron Cultures. Free Radic. Biol. Med. 2019, 130, 471- 477.

86) Platnich, C. M.; Hariri, A. A.; Rahbani, J. F.; Gordon, J. B; Sleiman, H. F.; Cosa, G. Kinetics of Strand Displacement and Hybridization on Wireframe DNA Nanostructures: Dissecting the Roles of Size, Morphology, and Rigidity. ACS Nano. 2018, 12, 12836-12846.

85) Glembockytė, V.; Frenette, M.; Mottillo, C.; Durantini, A. M.; Gostick, J.; Strukil, V.; Friščć, T.; Cosa, G. Highly Photostable and Fluorescent Microporous Solids Prepared via Solid-state Entrapment of BODIPY Dyes in a Nascent Metal-Organic Framework. J. Am. Chem. Soc. 2018, 140, 16882-16887.

84) Gidi, Y.; Bayram, S.; Ablenas, C.; Blum, A. S.; Cosa, G. Efficient One-step PEG-silane Passivation of Glass Surfaces for Single-molecule Fluorescence Studies. ACS App. Mater. Interfaces. 2018, 10, 39505-39511.

PEG protocol

83) Glembockytė, V.; Wieneke, R.; Gatterdam, K.; Gidi, Y.; Tampé, R.; Cosa, G. TrisNTA Fluorophore as a Self-Healing Dye for Single-Molecule Fluorescence Imaging. J. Am. Chem. Soc. 2018, 140, 11006-11012.

82) Bacellar, I. O. L.; Oliveira, M. C.; Dantas, L. S.; Costa, E. B.; Junqueira, H. C.; Martins, W. K.; Durantini, A. M.; Cosa, G.; Mascio, P. D.; Wainwright, M.; Miotto, R.; Cordeiro, R. M.; Miyamoto, S.; Baptista, M. S. Photosensitized Membrane Permeabilization Requires Contact-Dependent Reactions Between Photosensitizer and Lipids. J. Am. Chem. Soc. 2018, 140, 9606-9615.

81) Greene, L. E.; Lincoln, R.; Cosa, G. Spatio-temporal Monitoring of Lipid Peroxyl Radicals in Live Cell Studies Combining Fluorogenic Antioxidants and Fluorescence Microscopy Methods. Free Radic. Biol. Med. 2018, 128, 124-136.

80) Wong, F. H.; AbuArish, A.; Matthes, E.; Turner, M. J.; Greene, L. E.; Cloutier, A.; Robert, R.; Thomas, D. Y; Cosa, G.; Cantin, A. M.; Hanrahan, J. W. Cigarette Smoke Activates CFTR through ROS-stimulated cAMP Signaling in Human Bronchial Epithelial Cells. Am. J. Physiol., Cell Physiol. 2018, 314, C118-C134.

79) Rahbani, J. F.; Vengut-Climent, E.; Chidchob, P.; Gidi, Y.; Trinh, T.; Cosa, G.; Sleiman, H. F. DNA Nanotubes with Hydrophobic Environments: Toward New Platforms for Guest Encapsulation and Cellular Delivery. Adv. Healthc. Mater. 2018, 7, 1701049.

78) Greene, L. E.; Lincoln, R.; Krumova, K.; Cosa, G. Development of a Fluorogenic Reactivity-Palette for the Study of Nucleophilic Addition Reactions Based on meso-Formyl BODIPY Dyes. ACS Omega. 2017, 2, 8618-8624.

77) Calver, C.; Lago, B. A.; Schanze, K. S.; Cosa, G. Enhancing the Photostability of Poly(phenylene ethynylene) for Single Particle Studies. Photochem. Photobiol. Sci. 2017, 16, 1821-1831.

76) Lincoln, R.; Greene, L. E.; Zhang, W.; Louisia, S.; Cosa, G. Mitochondria Alkylation and Cellular Trafficking Mapped with a Lipophilic BODIPY-acrolein Fluorogenic Probe. J. Am. Chem. Soc. 2017, 139, 16273-16281.

75) Greene, L. E.; Lincoln, R.; Cosa, G. Rate of Lipid Peroxyl Radical Production During Cellular Homeostasis Unravelled Via Fluorescence Imaging. J. Am. Chem. Soc. 2017, 139, 15801-15811.

74) Glembockytė, V.; Cosa, G. Redox–Based Photostabilizing Agents in Fluorescence Imaging; the Hidden Role of Intersystem Crossing in Geminate Radical Ion Pairs. J. Am. Chem. Soc. 2017, 139, 13227-13233.

73) Hariri, A.; Hamblin, G. D.; Hardwick, J. S.; Godin, R.; Desjardins, J.-F.; Wiseman, P. W.; Sleiman, H. F.; Cosa, G. Stoichiometry and Dispersity of DNA Nanostructures Using Photobleaching Pair-Correlation Analysis. Bioconjugate Chem. 2017, 28, 2340-2349.

72) Gidi, Y.; Götte, M.; Cosa, G. Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method. J. Phys. Chem. B. 2017, 121, 2039-2048.

71) Lincoln, R.; Durantini, A. M.; Greene, L. E.; Martínez, S. R.; Knox, R.; Becerra, M. C.; Cosa, G. meso-Acetoxymethyl BODIPY Dyes for Photodynamic Therapy: Improved Photostability of Singlet Oxygen Photosensitizers. Photochem. Photobiol. Sci. 2017, 16, 178-184.

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70) Ablenas, C.; Liu, H. W.; Shkriabai, N.; Kvaratskhelia, M.; Cosa, G.; Götte, M. Dynamic Interconversions of HCV Helicase Binding Modes on its Nucleic Acid Substrate. ACS Infect. Dis. 2017, 3, 99-109.

69) Belzile, M. N.; Godin, R.; Durantini, A. M.; Cosa, G. Monitoring Chemical and Biological Electron Transfer Reactions with a Fluorogenic Vitamin K Analogue Probe. J. Am. Chem. Soc. 2016, 138, 16388-16397.

68) Calver, C. F.; Schanze, K. S.; Cosa, G. Biomimetic Light Harvesting Antenna Based on the Self-Assembly of Conjugated Polyelectrolytes Embedded within Lipid Membranes. ACS Nano. 2016, 10, 10598-10605.

67) Glembockytė, V.; Lin, J.; Cosa, G. Improving the Photostability of Red- and Green-Emissive Single-Molecule Fluorophores via Ni2+ Mediated Excited Triplet-State Quenching. J. Phys. Chem. B. 2016, 120, 11923-11929.

66) Ngure, M.; Issur, M.; Shkriabai, N.; Liu, H. W.; Cosa, G. Kvaratskhelia, M.; Götte, M.; Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and viral RNA Show Extensive Overlap. ACS Infect. Dis. 2016, 2, 839-851.

65) Greene, L. E.; Godin, R.; Cosa, G. Fluorogenic Ubiquinone Analogue for Monitoring Chemical and Biological Redox Processes. J. Am. Chem. Soc. 2016, 138, 11327-11334.

64) Godin, R.; Cosa, G. Counting Single Redox Turnovers: Fluorogenic Antioxidant Conversion and Mass Transport Visualization via Single Molecule Spectroelectrochemistry. J. Phys. Chem. C. 2016, 120, 15349-15353.

63) Durantini, A.; Greene, L. E.; Lincoln, R.; Martinez, S.; Cosa, G. Reactive Oxygen Species Mediated Activation of a Dormant Singlet Oxygen Photosensitizer: From Autocatalytic Singlet Oxygen Amplification to Chemicontrolled Photodynamic Therapy. J. Am. Chem. Soc. 2016, 138, 1215-1225.

62) Rahbani, J. F.; Hariri, A. A.; Cosa, G.; Sleiman, H. F. Dynamic DNA Nanotubes: Reversible Switching between Single and Double-Stranded Forms, and Effect of Base Deletions. ACS Nano. 2015, 9, 11898-11908.

61) Godin, R.; Sherman, B.; Bergkamp, J.; Chesta, C., A.; Moore, A.; Moore, T; Palacios, R. E.; Cosa, G. Charge Transfer Dynamics of Fluorescent Dye-Sensitized Electrodes under Applied Biases. J. Phys. Chem. Lett. 2015, 6, 2688-2693.

60) Li, L.; Liu, W.; Zeng, H.; Mu, X.; Cosa, G.; Mi, Z.; Li, C.-J. Photo-Induced Metal Catalyst Free Aromatic Finkelstein Reaction. J. Am. Chem. Soc. 2015, 137, 8328-8331.

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59) Calver, C. F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir. 2015, 31, 11842-11850.

ACS Editor's Choice

58) Godin, R.; Palacios, R.; Cosa, G. Heterogeneous Charge Mobility in Individual Conjugated Polyelectrolyte Nanoparticles Revealed by Two-Color Single Particle Spectroelectrochemistry Studies. J. Phys. Chem. C. 2015, 119, 12875-12886.

57) Lincoln, R.; Greene, L.; Bain, C.; Flores-Rizo, J. O.; Bohle, D. S.; Cosa, G. When Push Comes to Shove: Unravelling the Mechanism and Scope of Non-emissive meso-Unsaturated BODPY dyes. J. Phys. Chem. B. 2015, 119, 4758-4765.

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56) Hariri, A. A.; Hamblin, G.; Gidi, Y.; Sleiman, H. F.; Cosa, G. Stepwise Growth of Surface-grafted DNA Nanotubes Visualized at the Single Molecule Level. Nature Chem. 2015, 7, 295-300.

55) Glembockytė, V.; Lincoln, R.; Cosa, G. Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. J. Am. Chem. Soc. 2015, 137, 1116-1122.

54) Godin, R.; Liu, H.-W.; Smith, L.; Cosa, G. Dye Lipophilicity and Retention in Lipid Membranes: Implications for Single Molecule Spectroscopy. Langmuir. 2014, 30, 11138-11146

53) Karam, P.; Hariri, A.A.; Calver, C.F.; Zhao, X; Schanze, K.S.; Cosa, G. Interaction of Anionic Phenylene Ethynylene Polymers with lipids: from membrane embedding to liposome fusion. Langmuir. 2014, 30, 10704-10711.

52) Lincoln, R.; Greene, L. E.; Krumova, K..; Ding, Z.; Cosa, G. Electronic Excited State Redox Properties for BODIPY Dyes Predicted from Hammett Constants: Estimating the Driving Force of Photoinduced Electron Transfer. J. Phys. Chem. A. 2014, 118, 10622-10630

51) Godin, R.; Liu, H.-W.; Cosa, G. Ambient Condition Oxidation in Individual Liposomes Observed at the Single Molecule Level. Chem. Sci. 2014, 5, 2525-2529.

50) Karam, P.; Powdrill, M. H.; Liu, H.-W.; Vasquez, C.; Mah, W.; Bernatchez, J.; Götte, M.; Cosa, G. Dynamics of HCV RNA-dependent RNA Polymerase NS5B in Complex with RNA. J. Biol. Chem. 2014, 289, 14399-14411.

49) Krumova, K.; Greene, L, E.; Cosa, G. Fluorogenic α-Tocopherol Analogue for Monitoring the Antioxidant Status within the Inner Mitochondrial Membrane of Live Cells. J. Am. Chem. Soc. 2013, 135, 17135-17143.

48) Krumova, K.; Cosa, G. Fluorogenic Probes for Imaging Reactive Oxygen Species. Photochemistry. 2013, 41, 279-301.

47) Llansola Portoles, M. J.; Bergkamp. J.; Tomlin, J.; Moore, T. A.; Gerdenis, K.; Moore, A. L.; Cosa, G.; Palacios, R. E. Photoinduced Electron Transfer in Perylene TiO2 Nanoassemblies. Photochem. Photobiol. 2013, 89, 1375-1382.

46) Frenette, M.; Cosa, G.; Friščć, T. Characterization of Organic Solid Forms and Real-time In Situ Monitoring of their Transformations Using Solid-state Fluorescence. Cryst. Eng. Comm. 2013, 15, 5100-5106

45) Hamblin, G.; Hariri, A.; Carneiro, C.; Lau, K. L.; Cosa, G.; Sleiman, H. F. A Simple Design for DNA Nanotubes from a Minimal Set of Unmodified Strands: Rapid, Room Temperature Assembly and Readily Tunable Structure. ACS Nano. 2013, 7, 3022-3028

44) Marko, R.; Liu, H.-W.; Ablenas, C. J.; Ehteshami, M.; Götte, M.; Cosa; G. Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV-1 Reverse Transcriptase on DNA-DNA Substrates at the Single-Molecule Level. j. Phys. Chem. B. 2013, 117, 4560-4567.

43) Li, B.; Harjani, J. R.; Cormier, N. S.; Madarati, H.;Atkinson, J.; Cosa, G.; Pratt. D. A. Besting Vitamin E: Sidechain Substitution is Key to the Reactivity of Naphthyridinol Antioxidants in Lipid Bilayers. J. Am. Chem. Soc. 2013, 135, 1394-1405.

42) Hernández, L. I.; Godin, R.; Bergkamp, J. J.; Llansola Portolés, M. j.; Sherman, B. D.; Tomlin, J.; Kodis, G.; Méndez-Hernández, D. D.; Bertolotti, S.; Chesta, C. A.; Mariño-Ochoa, E.; Moore, A. L.; Moore, T.; Cosa, G.; Palacios. R. E. Spectral Characteristics and Photosensitization of TiO2 Nanoparticles in Reverse Micelles by Perylenes. J. Phys. Chem. B. 2013, 117, 4568-4581.

41) Krumova, K.; Friedland, S.; Cosa, G. How Lipid Unsaturation, Peroxyl Radical Partitioning and Chromanol lipophilic Tail Affect the Antioxidant Activity of α-Tocopherol: Direct Visualization via High Throughput Fluorescence Studies Conducted with Fluorogenic α-Tocopherol Analogues. J. Am. Chem. Soc. 2012, 134, 10102-10113.

40) Menard, A.; Huang, Y.; Karam, P.; Cosa, G.; Auclair, K. Site-specific Fluorescent Labelling and Oriented-immobilization of a Triple Mutant of CYP3A4 via C64. Bioconjugate Chem. 2012, 23, 826-836.

39) Liu, H.-W.; Ngo, A. T.; Cosa, G. Enhancing the Emissive Properties of PPV Conjugated Polyelectrolyte-coated SiO2 Nanoparticles. J. Am. Chem. Soc. 2012, 134, 1648-1652.

38) Borozenko, O.; Godin, R.; Lau, K. L.; Mah, W.; Cosa, G.; Skene, W. G.; Giasson, S., R. Real-Time Fluorimetric Degrafting Detection of Covalently Attached Fluorescent Polymer Brushes from Silica Substrates- Effects of pH and Salt Concentration. Macromolecules. 2011, 44, 8177-8184.

37) Bergkamp, J. J.; Sherman, B. D.; Mariño-Ochoa, E.; Palacios, R. E.; Cosa, G.; Moore, T. A.; Gust, D.; Moore, A. L. Synthesis and characterization of octabutoxy silicon phthalocyanines bearing simiconducting metal oxide anchoring groups via a phenoxy linkage. J. P. P. 2011, 15, 1-8.

36) Kostikov, A. P.; Iovkova, L.; Chin, J.; Schirrmacher, E.; Wängler, B.; Wängler, C.; Jurkschat, K.; Cosa, G.; Schirrmacher, R. N-(4-(di-tert-butyl[18F]fluorosilyl)benzyl)-2-hydroxy-N,N-dimethylethylammonium bromide ([18F]SiFAN+Br-): A novel lead compound for the development of hydrophilic SiFA-based prosthetic groups for 18F-labeling. J. Fluorine Chem. 2011, 132, 27-34.

35) Ngo, A. T.; Karam, P.; Cosa, G. Conjugated polyelectrolyte-lipid interactions: Opportunities in biosensing (Invited review for the special issue "Perspectives and Challenges for the International Year of Chemistry"). Pure Appl. Chem. 2011, 83, 43-55.

34) Krumova, K.; Cosa, G. BODIPY Dyes with Tunable Redox Potentials and Functional Groups for Further Tethering: Preparation, Electrochemical and Spectroscopic Characterization. J. Am. Chem. Soc. 2010, 132, 17560-17569.

33) Karam, P.; Ngo, A. T.; Rouiller, I.; Cosa, G. Unraveling Electronic Energy Transfer in Single Conjugated Polyelectrolytes Encapsulated in Lipid Vesicles. Proc. Nat. Acad. Sci. USA. 2010, 107, 17480-17485.

32) Ngo, A. T.; Lau, K. L.; Quesnel, J. S.; Aboukhalil, R.; Cosa, G. Deposition of the Anionic Conjugated Polyelectrolyte Poly(phenylenevinylene) onto Silica Nanoparticles via Electrostatic Interactions: Assembly and Single Particle Spectroscopy (special issue in honor of J. C. (Tito) Scaiano). Can. J. Chem.2011, 89, 381-384.

31) Solís. C.; Grosso, V.; Faggioli, N.; Cosa, G.; Romero, M.; Previtali, C.; Montejano, H.; Chesta, C. A. Solvent and Temperature Effects on the Emission Spectra of Excited CT States. A Simple Method for the Experimental Estimation of the Solvent Reorganization Energy. Photochem. Photobiol. Sci. 2010, 9, 675-686.

30) Lo, P.; Karam, P.; Aldaye, F.; Hamblin, G.; Cosa, G.; Sleiman, H. F. Loading and Selective Release of Cargo in DNA Nanotubes with Longitudinal Variation. Nature Chem. 2010, 2, 319-328.

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29) Ngo, A. T.; Cosa, G. Assembly of Zwitterionic Phospholipid/Conjugated Polyelectrolyte Complexes: Structure and Photophysical Properties. Langmuir. 2010, 26, 6746-6754.

28) Khatchadourian, A.; Krumova, K.; Boridy, S.; Ngo, A. T.; Maysinger, D.; Cosa, G. Molecular Imaging of Lipid-Peroxyl Radicals in Living Cells with a Bodipy-α-tocopherol Adduct. Biochemistry. 2009, 48, 5658 - 5668.

27) Krumova, K.; Oleynik, P.; Karam, P.; Cosa, G. Phenol-based Lipophilic Fluorescent Antioxidant Indicators: a Rational Approach. J. Org. Chem. 2009, 74, 3641 - 3651.

26) Aldaye, F. A.; Lo, P. K.; Karam, P.; McLaughlin, C. K.; Cosa, G.; Sleiman, H. F. Modular Construction of DNA Nanotubes of Tunable Geometry and Single- or Double-stranded Character. Nature Nanotech. 2009, 4, 349-352.

Highlighted in:

25) Cosa, G.; Lukeman, M.; Scaiano, J. C. How Drug Photodegradation Studies Led to the Promise of New Therapies and Some Fundamental Reaction Dynamics along the Way. scc. Chem. Res. 2009, 42, 599 - 607.

24) Cosa, G.; Scaiano, J. C. Reactivity of Adrenaline toward Alkoxyl Radicals and Carbonyl Triplet States. Org. Biomol. Chem. 2008, 6, 4609 - 4614.

23) Ngo, A. T.; Karam, P.; Fuller, E.; Burger, M; Cosa, G. Liposome Encapsulation of Conjugated Polyelectrolytes: Toward a Liposome Beacon. J. Am. Chem. Soc. 2008, 130, 457-459.

22) Oleynik, P.; Ishihara, Y.; Cosa, G. Design and Synthesis of a BODIPY-α-Tocopherol Adduct for Use as an Off/On Fluorescent Antioxidant Indicator. J. Am. Chem. Soc. 2007, 129, 1842-1843.

Highlighted in:

21) Cosa, G.; Zeng, Y.; Liu, H.-W.; Landes, C. F.; Makarov, D.; Musier-Forsyth, K.; Barbara, P. F. Evidence for Non-Two-State Kinetics in the Nucleocapsid Protein Chaperoned Opening of DNA Hairpins. J. Phys. Chem. B. 2006, 110, 2419-2426.

20) Liu, H.-W.; Cosa, G.; Landes, C. F.; Zeng, Y.; Kovaleski, B. J.; Mullen, D. G.; Barany, G.; Musier-Forsyth, K.;. Barbara, P. F. Single Molecule FRET Studies of Important Intermediates in the Nucleocapsid Protein Chaperoned Minus-Strand Transfer Step in HIV-1 Reverse transcription. Biophys. J. 2005, 89, 3470-3479.

19) Cosa, G.; Harbron, E. J.; Zeng, Y.; Liu, H.-W.; O'Connor, D. B.; Eta, C.; Musier-Forsyth, K.; Barbara, P. F. Secondary Structure and Secondary Structure Dynamics of DNA Hairpins Complexed with HIV-1 NC Protein. Biophys. J. 2004, 87, 2759-2767.

18) Cosa, G. Photodegradation and Photosensitization in Pharmaceutical Products: Assessing Drug Phototoxicity. Pure Appl. Chem. 2004, 76, 263-275.

17) Llauger, L.; Miranda, M. A.; Cosa, G.; Scaiano, J. C. Comparative Study of the Reactivities of Different Aroyl-substituted Benzyl Carbanions in Water and DMSO. J. Org. Chem. 2004, 69, 7066-7071.

16) Cosa, G.; Scaiano, J. C. Laser Techniques in the Study of Drug Photochemistry. Photochem. Photobiol. 2004, 80, 159-174.

15) Cosa, G.; Scaiano, J. C. Photochemistry of Diketones: Observation of a Triplet State-oxygen Adduct. J. Am. Chem. Soc. 2004, 126, 8636-8637.

14) Llauger, L.; Cosa, G.; Scaiano, J. C. First Determination of Absolute Rate Constants for the Reaction of Aroyl-substituted Benzyl Carbanions in Water and DMSO. J. Am. Chem. Soc. 2002, 124, 15308-15312.

13) Cosa, G.; Galletero, M. S.; Fernández, L.; Márquez, F.; García, H.; Scaiano, J. C. Tuning the Photocatalytic Activity of Titanium Dioxide by Encapsulation Inside Zeolites Exemplified by the Cases of Thianthrene Photooxygenation and Horseradish Peroxidase Photodeactivation. New J. Chem. 2002, 26, 1448-1455.

12) Cosa, G.; Vinnete, A. L.; McLean, J. R. N.; Scaiano, J. C. Novel DNA Damage Detection Technique Applying Time-resolved Fluorescence Measurements. Anal. Chem. 2002, 74, 6163-6169.

11) Chrétien, M. N.; Cosa, G.; García, H.; Scaiano, J. C. Increasing the Life Expectancy of Carbanions by Zeolite Inclusion. Chem. Commun. 2002, 2154-2155.

10) Boscá, F.; Cosa, G.; Miranda, M. A.; Scaiano, J. C. Inversion of 4-Methoxybenzophenone Triplet in Aqueous Solutions. Photochem. Photobiol. Sci. 2002, 1, 704-709.

9) Cosa, G.; Llauger, L.; Scaiano, J. C.; Miranda, M. A. Absolute Rate Constants for Water Protonation of 1-(3-Benzoylphenyl)alkyl Carbanions. Org. Lett. 2002, 4, 3083-3085.

8) Cosa, G.; Chrétien, M. N.; Galletero, M. S.; Fornés, V.; García, H.; Scaiano, J. C. Photocatalytic Activity of a Multi-component System Assembled within Zeolites. Case of 2,4,6-Triphenylpyrylium or Ruthenium Trisbipyridyl Photosensitizers and Titanium Dioxide Relays within Zeolite Y. J. Phys. Chem. B. 2002, 106, 2460-2467.

7) Cosa, G.; Purohit, S.; Boscá, F.; Miranda, M. A.; Scaiano, J. C. A Laser Flash Photolysis Study of Fenofibric Acid in Aqueous Buffered Media. Unexpected Triplet State Inversion in a Derivative of 4-alkoxybenzophenone. Photochem. Photobiol. 2002, 75, 193-200.

6) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; McNamee, J. P.; Scaiano, J. C. Photophysical Properties of DNA-stain Dyes Bound to Double and Single Stranded DNA in Aqueous Buffered Solution. Photochem. Photobiol. 2001, 73, 585-599.

5) Corrent S.; Cosa, G.; Scaiano, J. C.; Galletero M. S.; Alvaro, M. A.; Garcia, H. Intrazeolite Photochemistry 26. Photophysical Properties of Nanosized TiO2 Clusters Included in Zeolites Y, Beta and Mordenite. Chem. Mater. 200113, 715-722.

4) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; Scaiano, J. C. Direct Determination of Single-to-Double Stranded DNA Ratio in Solution Applying Time-resolved Fluorescence Measurements of Dye-DNA Complexes. Chem. Commun. 2000, 689-690.

3) Sortino S.; Cosa, G.; Scaiano, J. C. pH Effect on the Efficiency of the Photodeactivation Pathways of Naphazoline: a Combined Steady State and Time Resolved Study. New J. Chem. 2000, 24, 159-163.

2) Cosa, G.; Martínez, L. J.; Scaiano, J. C. Influence of Solvent Polarity and Base Concentration on the Photochemistry of Ketoprofen: Independent Singlet and Triplet Pathways. Phys. Chem. Chem. Phys. 1999, 1, 3533-3537.

1) Cosa, G.; Chesta, C. A. Estimation of the Bimolecular Rate Constant for Exciplex Formation from the Analysis of its Emission Spectrum. J. Phys. Chem. A. 1997, 101, 4922-4928.

Book Chapters

Book Cover

1) Krumova, K.; Cosa, G.; Overview of Reactive Oxygen Species. In "Singlet Oxygen: Applications in Biosciences and Nanosciences" Nonell, S.; Clors, C.; Royal Society of Chemistry, Cambridge. 2015.

Patents

1) Cosa, G.; Durantini, A. M.; Greene, L. E.; Lincoln, R.; Photodynamic therapy photosensitizers. US Patent App. 15/404,763, 2017.

News and Views

5) Greene, L. E.; Krumova, K.; Godin, R.; Lincoln, R.; Cosa, G.; European Photochemical Association (EPA) Newsletter, Special Report on Fluorogenic Probes. 2014, 60-65.

4) Cosa, G.; Single-molecule fluorescence: Assembling nanoantennas. Nat. Chem. 5, 2013, 159-160.

3) Cosa, G.; PROFILE: Early Excellence in Physical Organic Chemistry. J. Phys. Org. Chem. 25, 2012, 732.

2) Braslavsky, S.; Cosa, G.; Sherman, B.; Thomas, A.; Introduction to the Symposium‐in‐Print: 21st Conference of the Inter‐American Photochemical Society, Mendoza, Argentina, May 2011. Photochem. Photobiol. 88, 2012, 761.

1) Krumova, K.; Cosa, G.; Novel probes for visualizing reactive oxygen species in lipid membranes. Proc. SPIE 7674, 2010, 767406/1-8.