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115) Patricia Islas, Casey M. Platnich, Yasser Gidi, Ryan Karimi, Lorianne Ginot, Daniel Saliba, Xin Luo, Gonzalo Cosa, Hanadi F. Sleiman. Automated Synthesis of DNA Nanostructures. Adv. Mater. 2024 https://doi.org/10.1002/adma.202403477

114) Michael D. Dore, Muhammad Ghufran Rafique, Tianxiao Peter Yang, Marlo Zorman, Casey M. Platnich, Pengfei Xu, Tuan Trinh, Felix J. Rizzuto, Gonzalo Cosa, Jianing Li, Alba Guarné & Hanadi F. Sleiman. Heat-activated growth of metastable and length-defined DNA fibers expands traditional polymer assembly. Nat. Commun. 2024, 15, 4384

113) Antonius T. M. Van Kessel and Gonzalo Cosa. Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis Proc. Nat. Acad. Sci. USA. 2024, 121, 21 e2317616121

112) McCain, J.; Martinez, S.R.; Fungo, F.; Sakaya, S.; Cosa, G. Two-Pronged Dormant Photosensitizer-Antibiotic Bacterial Inactivation: Mechanism, Dosage, and Cellular Evolution Visualized at the Single-Cell Level. J. Am. Chem. Soc. 2023, 145, 51, 28124-28136

111) Gidi, Y.; Ramos-Sanchez, J.; Lovell, T.C.; Glembockyte, V.; Cheah, I.K.; Schnermann, M.; Halliwell, B.; Cosa, G. Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids. J. Am. Chem. Soc. 2023, 145, 36, 19571-19577

110) Luo, X.; Saliba, D.; Yang, T.; Gentile, S.; Mori, K.; Islas Garcia, P.; Das, T.; Bagheri, N.; Porchetta, A.; Guarne, A.; Cosa, G.; Sleiman, H.F. Minimalist Design of Wireframe DNA Nanotubes: Tunable Geometry, Size, Chirality, and Dynamics. Angew. Chem. Int. Ed. 2023, 62, e202309869.

109) Gidi, Y.; Robert, A.; Tordo, A.; Lovell, T.C.; Ramos-Sanchez, J.; Sakaya, A.; Matthias, G.; Cosa, G. Binding and Sliding Dynamics of the Hepatitis C Virus Polymerase: Hunting the 3′ Terminus. ACS Infect. Dis. 2023, 9,8, 1488-1490.

108) Sosa, M.J.; Fonseca, J.L.; Sakaya, A.; Urrutia, M.N.; Petroselli, G.; Erra-Balsells, R.; Quindt, M.I.; Bonesi, S.M.; Cosa, G.; Vignoni, M.; Thomas, A.H. Alkylation converts riboflavin into an efficient photosensitizer of phospholipid membranes. Biochim. Biophys. Acta Biomembr. 2023, 1865 (5), 184155

107) Castillo-Pazos, D.J.; Lasso, J.D.; Hamzehpoor, E.; Ramos-Sanchez, J.; Salgado, J.M.; Cosa, G.; Perepichka, D.F.; Li, C.J. Triarylamines as catalytic donors in light-mediated electron donor–acceptor complexes. Chem. Sci. 2023, 14, 3470-3481.

106) Sakaya, A.; Bacellar, I.O.L.; Fonseca, J.L.; Durantini, A.; McCain, J.; Xu, L.; Vignoni, M.; Thomas, A.H.; Baptista, M.; Cosa, G. Singlet oxygen flux, associated lipid phooxidation, and membrane expansion dynamics visualized on giant unilamellar vesicles. Langmuir. 2023, 39, 1, 442-452.

105) Van Kessel, A.T.M.; Karimi, R.; Cosa, G. Live-cell imaging reveals impaired detoxification of a lipid-derived electrophiles is a hallmark of ferropotosis. Chem. Sci. 2022, 13, 9727-9738.

104) Naguib, M.; Feldman, N.; Zarodkiewicz, P.; Shropshire, H.; Biamis, C.; El-Halfawy, O.; McCain, J.; Dezanet, C.; Décout, J.; Chen, Y.; Cosa, G.; Valvano, M. An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria. PLoS Biol. 2022, 20 (5).

103) Sakaya, A.; Durantini, A.M.; Gidi, Y.; Šverko, T.; Wieczny, V.; McCain, J.; Cosa, C. Fluorescence-Amplified Detection of Redox Turnovers in Supported Lipid Bilayers Illuminates Redox Processes of α-Tocopherol. ACS Applied Materials & Interfaces. 2022, 14, 11, 13872-13882.

102) Lincoln, R.; Zhang, W.; Lovell, T.C.; Jodko-Piórecka, K.; Devlaminck, P.A.; Sakaya, A.; Van Kessel, A.; Cosa, G. Chemically Tuned, Reversible Fluorogenic Electrophile for Live Cell Nanoscopy. ACS Sensors. 2022, 7, 1, 166-174.

101) Hamzepoor, E.; Ruchlin, C.; Tao, Y.; Ramos-Sanchez J.E.; Titi, H.M.; Cosa, G.; Perepichka, D.F. Room temperature phosphorescence vs triplet−triplet annihilation in N substituted acridone solids. J. Phys. Chem. Lett. 2021, 12, 27, 6431-6438.

100) Rizzuto, F.; Platnich, C.M.; Luo, X.; Dore, M.L.; Lachance-Brais, C.; Cosa G.; Sleiman, H.F. A dissipative pathway for the structural evolution of DNA fibers. Nature Chem. 2021, 13, 843-849.

99) Dore, M.D.; Trinh, T.; Zorman, M.; de Rochambeau, D.; Platnich, C.M.; Xu, P.; Luo, X.; Remington, J.; Toader, V.; Cosa, G.; Li, J.; Sleiman, H.F. Thermosetting supramolecular polymerization of compartmentalized DNA fibers with stereo-sequence and length control. Chem. 2021, 7, 9, 2395-2414.

98) Lincoln, R.; Foret, M.K.; Do Carmo, S.; Cuello, A.; Cosa, G. FOCUS REVIEW - Connecting The ‘Dots’: From Free Radical Lipid Oxidation to Cell Pathology and Disease. Chem. Rev. 2020, 120, 12757-12787.

Journal Cover

97) Martinez, S.R.; Durantini, A.M.; Becerra, M.C.; Cosa, G. Real-Time Single-Cell Imaging Reveals Accelerating Lipid Peroxyl Radical Formation in Escherichia coli Triggered by a Fluoroquinolone Antibiotic. ACS Infect. Dis. 2020, 6, 2468-2477.

96) Gidi, Y.; Payne, L.; Glembockyte, V.; Michie, M.; Schnermann M, Cosa G. Unifying mechanism for thiol induced photoswitching and photostability of cyanine dyes. J. Am. Chem. Soc. 2020, 142, 12681-12689.

95) Platnich, C.; Rizutto, F.; Cosa, G.; Sleiman, H.F. Single-molecule methods in structural DNA nanotechnology. Chem. Soc. Rev. 2020, 49, 4220-4233.

94) Isselstein, M.; Zhang, L.; Glembockyte, V.; Brix, O.; Cosa, G.; Tinnefeld, P.; Cordes, T. Self-Healing Dyes – Keeping the Promise? J. Phys. Chem. Lett. 2020, 11, 4462-4480.

93) Dastpeyman, S.; Godin, R.; Cosa, G.; English, A. Quantifying Heme-Protein Maturation from Ratiometric Fluorescence Lifetime Measurements on the Single Fluorophore in Its GFP Fusion. J. Phys. Chem. A. 2020, 124, 746-754.

92) Platnich, C.; Hariri, A.; Sleiman, H.; Cosa, G. Advancing Wireframe DNA Nanostructures Using Single-Molecule Fluorescence Microscopy Techniques. Acc. Chem. Res. 2019, 52, 3199-3210.

91) Ablenas, C.; Gidi, Y.; Powdrill, M.; Ahmed, N.; Shaw, T.; Mesko, M.; Götte, M.; Cosa, G.; Pezacki, J. Hepatitis C virus helicase binding and activity monitored through site-specific labeling using an expanded genetic code. ACS Infect. Dis. 2019, 5, 2118-2126.

90) Sehayek, S.; Gidi, Y.; Glembockyte, V.; Brandão, H.; François, P.; Cosa, G.; Wiseman, P. A High-Throughput Image Correlation Method for Rapid Analysis of Fluorophore Photoblinking and Photobleaching Rates. ACS Nano. 2019, 13, 11955-11966.

89) Lincoln, R.; Van Kessel A.T.M.; Zhang, W.; Cosa, G. A Dormant BODIPY-Acrolein Singlet Oxygen Photosensitizer Intracellularly Activated upon Adduct Formation with Cysteine Residues. Photochem. Photobiol. Sci. 2019, 18, 2003-2011.

88) Greene, L. E.; Lincoln, R.; Cosa, G. Tuning Photoinduced Electron Transfer Efficiency of Fluorogenic BODIPY‐α‐Tocopherol Analogues. Photochem. Photobiol. 2019, 95, 192-201.

87) Foret, M. K.; Do Carmo, S.; Lincoln, R.; Greene, L. E.; Zhang, W.; Cuello, A. C.; Cosa, G. Effect of Antioxidant Supplements on Lipid Peroxidation Leves in Primary Cortical Neuron Cultures. Free Radic. Biol. Med. 2019, 130, 471- 477.

86) Platnich, C. M.; Hariri, A. A.; Rahbani, J. F.; Gordon, J. B; Sleiman, H. F.; Cosa, G. Kinetics of Strand Displacement and Hybridization on Wireframe DNA Nanostructures: Dissecting the Roles of Size, Morphology, and Rigidity. ACS Nano. 2018, 12, 12836-12846.

85) Glembockytė, V.; Frenette, M.; Mottillo, C.; Durantini, A. M.; Gostick, J.; Strukil, V.; Friščć, T.; Cosa, G. Highly Photostable and Fluorescent Microporous Solids Prepared via Solid-state Entrapment of BODIPY Dyes in a Nascent Metal-Organic Framework. J. Am. Chem. Soc. 2018, 140, 16882-16887.

84) Gidi, Y.; Bayram, S.; Ablenas, C.; Blum, A. S.; Cosa, G. Efficient One-step PEG-silane Passivation of Glass Surfaces for Single-molecule Fluorescence Studies. ACS App. Mater. Interfaces. 2018, 10, 39505-39511.

PEG protocol

83) Glembockytė, V.; Wieneke, R.; Gatterdam, K.; Gidi, Y.; Tampé, R.; Cosa, G. TrisNTA Fluorophore as a Self-Healing Dye for Single-Molecule Fluorescence Imaging. J. Am. Chem. Soc. 2018, 140, 11006-11012.

82) Bacellar, I. O. L.; Oliveira, M. C.; Dantas, L. S.; Costa, E. B.; Junqueira, H. C.; Martins, W. K.; Durantini, A. M.; Cosa, G.; Mascio, P. D.; Wainwright, M.; Miotto, R.; Cordeiro, R. M.; Miyamoto, S.; Baptista, M. S. Photosensitized Membrane Permeabilization Requires Contact-Dependent Reactions Between Photosensitizer and Lipids. J. Am. Chem. Soc. 2018, 140, 9606-9615.

81) Greene, L. E.; Lincoln, R.; Cosa, G. Spatio-temporal Monitoring of Lipid Peroxyl Radicals in Live Cell Studies Combining Fluorogenic Antioxidants and Fluorescence Microscopy Methods. Free Radic. Biol. Med. 2018, 128, 124-136.

80) Wong, F. H.; AbuArish, A.; Matthes, E.; Turner, M. J.; Greene, L. E.; Cloutier, A.; Robert, R.; Thomas, D. Y; Cosa, G.; Cantin, A. M.; Hanrahan, J. W. Cigarette Smoke Activates CFTR through ROS-stimulated cAMP Signaling in Human Bronchial Epithelial Cells. Am. J. Physiol., Cell Physiol. 2018, 314, C118-C134.

79) Rahbani, J. F.; Vengut-Climent, E.; Chidchob, P.; Gidi, Y.; Trinh, T.; Cosa, G.; Sleiman, H. F. DNA Nanotubes with Hydrophobic Environments: Toward New Platforms for Guest Encapsulation and Cellular Delivery. Adv. Healthc. Mater. 2018, 7, 1701049.

78) Greene, L. E.; Lincoln, R.; Krumova, K.; Cosa, G. Development of a Fluorogenic Reactivity-Palette for the Study of Nucleophilic Addition Reactions Based on meso-Formyl BODIPY Dyes. ACS Omega. 2017, 2, 8618-8624.

77) Calver, C.; Lago, B. A.; Schanze, K. S.; Cosa, G. Enhancing the Photostability of Poly(phenylene ethynylene) for Single Particle Studies. Photochem. Photobiol. Sci. 2017, 16, 1821-1831.

76) Lincoln, R.; Greene, L. E.; Zhang, W.; Louisia, S.; Cosa, G. Mitochondria Alkylation and Cellular Trafficking Mapped with a Lipophilic BODIPY-acrolein Fluorogenic Probe. J. Am. Chem. Soc. 2017, 139, 16273-16281.

75) Greene, L. E.; Lincoln, R.; Cosa, G. Rate of Lipid Peroxyl Radical Production During Cellular Homeostasis Unravelled Via Fluorescence Imaging. J. Am. Chem. Soc. 2017, 139, 15801-15811.

74) Glembockytė, V.; Cosa, G. Redox–Based Photostabilizing Agents in Fluorescence Imaging; the Hidden Role of Intersystem Crossing in Geminate Radical Ion Pairs. J. Am. Chem. Soc. 2017, 139, 13227-13233.

73) Hariri, A.; Hamblin, G. D.; Hardwick, J. S.; Godin, R.; Desjardins, J.-F.; Wiseman, P. W.; Sleiman, H. F.; Cosa, G. Stoichiometry and Dispersity of DNA Nanostructures Using Photobleaching Pair-Correlation Analysis. Bioconjugate Chem. 2017, 28, 2340-2349.

72) Gidi, Y.; Götte, M.; Cosa, G. Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method. J. Phys. Chem. B. 2017, 121, 2039-2048.

71) Lincoln, R.; Durantini, A. M.; Greene, L. E.; Martínez, S. R.; Knox, R.; Becerra, M. C.; Cosa, G. meso-Acetoxymethyl BODIPY Dyes for Photodynamic Therapy: Improved Photostability of Singlet Oxygen Photosensitizers. Photochem. Photobiol. Sci. 2017, 16, 178-184.

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70) Ablenas, C.; Liu, H. W.; Shkriabai, N.; Kvaratskhelia, M.; Cosa, G.; Götte, M. Dynamic Interconversions of HCV Helicase Binding Modes on its Nucleic Acid Substrate. ACS Infect. Dis. 2017, 3, 99-109.

69) Belzile, M. N.; Godin, R.; Durantini, A. M.; Cosa, G. Monitoring Chemical and Biological Electron Transfer Reactions with a Fluorogenic Vitamin K Analogue Probe. J. Am. Chem. Soc. 2016, 138, 16388-16397.

68) Calver, C. F.; Schanze, K. S.; Cosa, G. Biomimetic Light Harvesting Antenna Based on the Self-Assembly of Conjugated Polyelectrolytes Embedded within Lipid Membranes. ACS Nano. 2016, 10, 10598-10605.

67) Glembockytė, V.; Lin, J.; Cosa, G. Improving the Photostability of Red- and Green-Emissive Single-Molecule Fluorophores via Ni2+ Mediated Excited Triplet-State Quenching. J. Phys. Chem. B. 2016, 120, 11923-11929.

66) Ngure, M.; Issur, M.; Shkriabai, N.; Liu, H. W.; Cosa, G. Kvaratskhelia, M.; Götte, M.; Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and viral RNA Show Extensive Overlap. ACS Infect. Dis. 2016, 2, 839-851.

65) Greene, L. E.; Godin, R.; Cosa, G. Fluorogenic Ubiquinone Analogue for Monitoring Chemical and Biological Redox Processes. J. Am. Chem. Soc. 2016, 138, 11327-11334.

64) Godin, R.; Cosa, G. Counting Single Redox Turnovers: Fluorogenic Antioxidant Conversion and Mass Transport Visualization via Single Molecule Spectroelectrochemistry. J. Phys. Chem. C. 2016, 120, 15349-15353.

63) Durantini, A.; Greene, L. E.; Lincoln, R.; Martinez, S.; Cosa, G. Reactive Oxygen Species Mediated Activation of a Dormant Singlet Oxygen Photosensitizer: From Autocatalytic Singlet Oxygen Amplification to Chemicontrolled Photodynamic Therapy. J. Am. Chem. Soc. 2016, 138, 1215-1225.

62) Rahbani, J. F.; Hariri, A. A.; Cosa, G.; Sleiman, H. F. Dynamic DNA Nanotubes: Reversible Switching between Single and Double-Stranded Forms, and Effect of Base Deletions. ACS Nano. 2015, 9, 11898-11908.

61) Godin, R.; Sherman, B.; Bergkamp, J.; Chesta, C., A.; Moore, A.; Moore, T; Palacios, R. E.; Cosa, G. Charge Transfer Dynamics of Fluorescent Dye-Sensitized Electrodes under Applied Biases. J. Phys. Chem. Lett. 2015, 6, 2688-2693.

60) Li, L.; Liu, W.; Zeng, H.; Mu, X.; Cosa, G.; Mi, Z.; Li, C.-J. Photo-Induced Metal Catalyst Free Aromatic Finkelstein Reaction. J. Am. Chem. Soc. 2015, 137, 8328-8331.

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59) Calver, C. F.; Liu, H.-W.; Cosa, G. Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir. 2015, 31, 11842-11850.

ACS Editor's Choice

58) Godin, R.; Palacios, R.; Cosa, G. Heterogeneous Charge Mobility in Individual Conjugated Polyelectrolyte Nanoparticles Revealed by Two-Color Single Particle Spectroelectrochemistry Studies. J. Phys. Chem. C. 2015, 119, 12875-12886.

57) Lincoln, R.; Greene, L.; Bain, C.; Flores-Rizo, J. O.; Bohle, D. S.; Cosa, G. When Push Comes to Shove: Unravelling the Mechanism and Scope of Non-emissive meso-Unsaturated BODPY dyes. J. Phys. Chem. B. 2015, 119, 4758-4765.

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56) Hariri, A. A.; Hamblin, G.; Gidi, Y.; Sleiman, H. F.; Cosa, G. Stepwise Growth of Surface-grafted DNA Nanotubes Visualized at the Single Molecule Level. Nature Chem. 2015, 7, 295-300.

55) Glembockytė, V.; Lincoln, R.; Cosa, G. Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. J. Am. Chem. Soc. 2015, 137, 1116-1122.

54) Godin, R.; Liu, H.-W.; Smith, L.; Cosa, G. Dye Lipophilicity and Retention in Lipid Membranes: Implications for Single Molecule Spectroscopy. Langmuir. 2014, 30, 11138-11146

53) Karam, P.; Hariri, A.A.; Calver, C.F.; Zhao, X; Schanze, K.S.; Cosa, G. Interaction of Anionic Phenylene Ethynylene Polymers with lipids: from membrane embedding to liposome fusion. Langmuir. 2014, 30, 10704-10711.

52) Lincoln, R.; Greene, L. E.; Krumova, K..; Ding, Z.; Cosa, G. Electronic Excited State Redox Properties for BODIPY Dyes Predicted from Hammett Constants: Estimating the Driving Force of Photoinduced Electron Transfer. J. Phys. Chem. A. 2014, 118, 10622-10630

51) Godin, R.; Liu, H.-W.; Cosa, G. Ambient Condition Oxidation in Individual Liposomes Observed at the Single Molecule Level. Chem. Sci. 2014, 5, 2525-2529.

50) Karam, P.; Powdrill, M. H.; Liu, H.-W.; Vasquez, C.; Mah, W.; Bernatchez, J.; Götte, M.; Cosa, G. Dynamics of HCV RNA-dependent RNA Polymerase NS5B in Complex with RNA. J. Biol. Chem. 2014, 289, 14399-14411.

49) Krumova, K.; Greene, L, E.; Cosa, G. Fluorogenic α-Tocopherol Analogue for Monitoring the Antioxidant Status within the Inner Mitochondrial Membrane of Live Cells. J. Am. Chem. Soc. 2013, 135, 17135-17143.

48) Krumova, K.; Cosa, G. Fluorogenic Probes for Imaging Reactive Oxygen Species. Photochemistry. 2013, 41, 279-301.

47) Llansola Portoles, M. J.; Bergkamp. J.; Tomlin, J.; Moore, T. A.; Gerdenis, K.; Moore, A. L.; Cosa, G.; Palacios, R. E. Photoinduced Electron Transfer in Perylene TiO2 Nanoassemblies. Photochem. Photobiol. 2013, 89, 1375-1382.

46) Frenette, M.; Cosa, G.; Friščć, T. Characterization of Organic Solid Forms and Real-time In Situ Monitoring of their Transformations Using Solid-state Fluorescence. Cryst. Eng. Comm. 2013, 15, 5100-5106

45) Hamblin, G.; Hariri, A.; Carneiro, C.; Lau, K. L.; Cosa, G.; Sleiman, H. F. A Simple Design for DNA Nanotubes from a Minimal Set of Unmodified Strands: Rapid, Room Temperature Assembly and Readily Tunable Structure. ACS Nano. 2013, 7, 3022-3028

44) Marko, R.; Liu, H.-W.; Ablenas, C. J.; Ehteshami, M.; Götte, M.; Cosa; G. Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV-1 Reverse Transcriptase on DNA-DNA Substrates at the Single-Molecule Level. j. Phys. Chem. B. 2013, 117, 4560-4567.

43) Li, B.; Harjani, J. R.; Cormier, N. S.; Madarati, H.;Atkinson, J.; Cosa, G.; Pratt. D. A. Besting Vitamin E: Sidechain Substitution is Key to the Reactivity of Naphthyridinol Antioxidants in Lipid Bilayers. J. Am. Chem. Soc. 2013, 135, 1394-1405.

42) Hernández, L. I.; Godin, R.; Bergkamp, J. J.; Llansola Portolés, M. j.; Sherman, B. D.; Tomlin, J.; Kodis, G.; Méndez-Hernández, D. D.; Bertolotti, S.; Chesta, C. A.; Mariño-Ochoa, E.; Moore, A. L.; Moore, T.; Cosa, G.; Palacios. R. E. Spectral Characteristics and Photosensitization of TiO2 Nanoparticles in Reverse Micelles by Perylenes. J. Phys. Chem. B. 2013, 117, 4568-4581.

41) Krumova, K.; Friedland, S.; Cosa, G. How Lipid Unsaturation, Peroxyl Radical Partitioning and Chromanol lipophilic Tail Affect the Antioxidant Activity of α-Tocopherol: Direct Visualization via High Throughput Fluorescence Studies Conducted with Fluorogenic α-Tocopherol Analogues. J. Am. Chem. Soc. 2012, 134, 10102-10113.

40) Menard, A.; Huang, Y.; Karam, P.; Cosa, G.; Auclair, K. Site-specific Fluorescent Labelling and Oriented-immobilization of a Triple Mutant of CYP3A4 via C64. Bioconjugate Chem. 2012, 23, 826-836.

39) Liu, H.-W.; Ngo, A. T.; Cosa, G. Enhancing the Emissive Properties of PPV Conjugated Polyelectrolyte-coated SiO2 Nanoparticles. J. Am. Chem. Soc. 2012, 134, 1648-1652.

38) Borozenko, O.; Godin, R.; Lau, K. L.; Mah, W.; Cosa, G.; Skene, W. G.; Giasson, S., R. Real-Time Fluorimetric Degrafting Detection of Covalently Attached Fluorescent Polymer Brushes from Silica Substrates- Effects of pH and Salt Concentration. Macromolecules. 2011, 44, 8177-8184.

37) Bergkamp, J. J.; Sherman, B. D.; Mariño-Ochoa, E.; Palacios, R. E.; Cosa, G.; Moore, T. A.; Gust, D.; Moore, A. L. Synthesis and characterization of octabutoxy silicon phthalocyanines bearing simiconducting metal oxide anchoring groups via a phenoxy linkage. J. P. P. 2011, 15, 1-8.

36) Kostikov, A. P.; Iovkova, L.; Chin, J.; Schirrmacher, E.; Wängler, B.; Wängler, C.; Jurkschat, K.; Cosa, G.; Schirrmacher, R. N-(4-(di-tert-butyl[18F]fluorosilyl)benzyl)-2-hydroxy-N,N-dimethylethylammonium bromide ([18F]SiFAN+Br-): A novel lead compound for the development of hydrophilic SiFA-based prosthetic groups for 18F-labeling. J. Fluorine Chem. 2011, 132, 27-34.

35) Ngo, A. T.; Karam, P.; Cosa, G. Conjugated polyelectrolyte-lipid interactions: Opportunities in biosensing (Invited review for the special issue "Perspectives and Challenges for the International Year of Chemistry"). Pure Appl. Chem. 2011, 83, 43-55.

34) Krumova, K.; Cosa, G. BODIPY Dyes with Tunable Redox Potentials and Functional Groups for Further Tethering: Preparation, Electrochemical and Spectroscopic Characterization. J. Am. Chem. Soc. 2010, 132, 17560-17569.

33) Karam, P.; Ngo, A. T.; Rouiller, I.; Cosa, G. Unraveling Electronic Energy Transfer in Single Conjugated Polyelectrolytes Encapsulated in Lipid Vesicles. Proc. Nat. Acad. Sci. USA. 2010, 107, 17480-17485.

32) Ngo, A. T.; Lau, K. L.; Quesnel, J. S.; Aboukhalil, R.; Cosa, G. Deposition of the Anionic Conjugated Polyelectrolyte Poly(phenylenevinylene) onto Silica Nanoparticles via Electrostatic Interactions: Assembly and Single Particle Spectroscopy (special issue in honor of J. C. (Tito) Scaiano). Can. J. Chem.2011, 89, 381-384.

31) Solís. C.; Grosso, V.; Faggioli, N.; Cosa, G.; Romero, M.; Previtali, C.; Montejano, H.; Chesta, C. A. Solvent and Temperature Effects on the Emission Spectra of Excited CT States. A Simple Method for the Experimental Estimation of the Solvent Reorganization Energy. Photochem. Photobiol. Sci. 2010, 9, 675-686.

30) Lo, P.; Karam, P.; Aldaye, F.; Hamblin, G.; Cosa, G.; Sleiman, H. F. Loading and Selective Release of Cargo in DNA Nanotubes with Longitudinal Variation. Nature Chem. 2010, 2, 319-328.

Highlighted in:

29) Ngo, A. T.; Cosa, G. Assembly of Zwitterionic Phospholipid/Conjugated Polyelectrolyte Complexes: Structure and Photophysical Properties. Langmuir. 2010, 26, 6746-6754.

28) Khatchadourian, A.; Krumova, K.; Boridy, S.; Ngo, A. T.; Maysinger, D.; Cosa, G. Molecular Imaging of Lipid-Peroxyl Radicals in Living Cells with a Bodipy-α-tocopherol Adduct. Biochemistry. 2009, 48, 5658 - 5668.

27) Krumova, K.; Oleynik, P.; Karam, P.; Cosa, G. Phenol-based Lipophilic Fluorescent Antioxidant Indicators: a Rational Approach. J. Org. Chem. 2009, 74, 3641 - 3651.

26) Aldaye, F. A.; Lo, P. K.; Karam, P.; McLaughlin, C. K.; Cosa, G.; Sleiman, H. F. Modular Construction of DNA Nanotubes of Tunable Geometry and Single- or Double-stranded Character. Nature Nanotech. 2009, 4, 349-352.

Highlighted in:

25) Cosa, G.; Lukeman, M.; Scaiano, J. C. How Drug Photodegradation Studies Led to the Promise of New Therapies and Some Fundamental Reaction Dynamics along the Way. scc. Chem. Res. 2009, 42, 599 - 607.

24) Cosa, G.; Scaiano, J. C. Reactivity of Adrenaline toward Alkoxyl Radicals and Carbonyl Triplet States. Org. Biomol. Chem. 2008, 6, 4609 - 4614.

23) Ngo, A. T.; Karam, P.; Fuller, E.; Burger, M; Cosa, G. Liposome Encapsulation of Conjugated Polyelectrolytes: Toward a Liposome Beacon. J. Am. Chem. Soc. 2008, 130, 457-459.

22) Oleynik, P.; Ishihara, Y.; Cosa, G. Design and Synthesis of a BODIPY-α-Tocopherol Adduct for Use as an Off/On Fluorescent Antioxidant Indicator. J. Am. Chem. Soc. 2007, 129, 1842-1843.

Highlighted in:

21) Cosa, G.; Zeng, Y.; Liu, H.-W.; Landes, C. F.; Makarov, D.; Musier-Forsyth, K.; Barbara, P. F. Evidence for Non-Two-State Kinetics in the Nucleocapsid Protein Chaperoned Opening of DNA Hairpins. J. Phys. Chem. B. 2006, 110, 2419-2426.

20) Liu, H.-W.; Cosa, G.; Landes, C. F.; Zeng, Y.; Kovaleski, B. J.; Mullen, D. G.; Barany, G.; Musier-Forsyth, K.;. Barbara, P. F. Single Molecule FRET Studies of Important Intermediates in the Nucleocapsid Protein Chaperoned Minus-Strand Transfer Step in HIV-1 Reverse transcription. Biophys. J. 2005, 89, 3470-3479.

19) Cosa, G.; Harbron, E. J.; Zeng, Y.; Liu, H.-W.; O'Connor, D. B.; Eta, C.; Musier-Forsyth, K.; Barbara, P. F. Secondary Structure and Secondary Structure Dynamics of DNA Hairpins Complexed with HIV-1 NC Protein. Biophys. J. 2004, 87, 2759-2767.

18) Cosa, G. Photodegradation and Photosensitization in Pharmaceutical Products: Assessing Drug Phototoxicity. Pure Appl. Chem. 2004, 76, 263-275.

17) Llauger, L.; Miranda, M. A.; Cosa, G.; Scaiano, J. C. Comparative Study of the Reactivities of Different Aroyl-substituted Benzyl Carbanions in Water and DMSO. J. Org. Chem. 2004, 69, 7066-7071.

16) Cosa, G.; Scaiano, J. C. Laser Techniques in the Study of Drug Photochemistry. Photochem. Photobiol. 2004, 80, 159-174.

15) Cosa, G.; Scaiano, J. C. Photochemistry of Diketones: Observation of a Triplet State-oxygen Adduct. J. Am. Chem. Soc. 2004, 126, 8636-8637.

14) Llauger, L.; Cosa, G.; Scaiano, J. C. First Determination of Absolute Rate Constants for the Reaction of Aroyl-substituted Benzyl Carbanions in Water and DMSO. J. Am. Chem. Soc. 2002, 124, 15308-15312.

13) Cosa, G.; Galletero, M. S.; Fernández, L.; Márquez, F.; García, H.; Scaiano, J. C. Tuning the Photocatalytic Activity of Titanium Dioxide by Encapsulation Inside Zeolites Exemplified by the Cases of Thianthrene Photooxygenation and Horseradish Peroxidase Photodeactivation. New J. Chem. 2002, 26, 1448-1455.

12) Cosa, G.; Vinnete, A. L.; McLean, J. R. N.; Scaiano, J. C. Novel DNA Damage Detection Technique Applying Time-resolved Fluorescence Measurements. Anal. Chem. 2002, 74, 6163-6169.

11) Chrétien, M. N.; Cosa, G.; García, H.; Scaiano, J. C. Increasing the Life Expectancy of Carbanions by Zeolite Inclusion. Chem. Commun. 2002, 2154-2155.

10) Boscá, F.; Cosa, G.; Miranda, M. A.; Scaiano, J. C. Inversion of 4-Methoxybenzophenone Triplet in Aqueous Solutions. Photochem. Photobiol. Sci. 2002, 1, 704-709.

9) Cosa, G.; Llauger, L.; Scaiano, J. C.; Miranda, M. A. Absolute Rate Constants for Water Protonation of 1-(3-Benzoylphenyl)alkyl Carbanions. Org. Lett. 2002, 4, 3083-3085.

8) Cosa, G.; Chrétien, M. N.; Galletero, M. S.; Fornés, V.; García, H.; Scaiano, J. C. Photocatalytic Activity of a Multi-component System Assembled within Zeolites. Case of 2,4,6-Triphenylpyrylium or Ruthenium Trisbipyridyl Photosensitizers and Titanium Dioxide Relays within Zeolite Y. J. Phys. Chem. B. 2002, 106, 2460-2467.

7) Cosa, G.; Purohit, S.; Boscá, F.; Miranda, M. A.; Scaiano, J. C. A Laser Flash Photolysis Study of Fenofibric Acid in Aqueous Buffered Media. Unexpected Triplet State Inversion in a Derivative of 4-alkoxybenzophenone. Photochem. Photobiol. 2002, 75, 193-200.

6) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; McNamee, J. P.; Scaiano, J. C. Photophysical Properties of DNA-stain Dyes Bound to Double and Single Stranded DNA in Aqueous Buffered Solution. Photochem. Photobiol. 2001, 73, 585-599.

5) Corrent S.; Cosa, G.; Scaiano, J. C.; Galletero M. S.; Alvaro, M. A.; Garcia, H. Intrazeolite Photochemistry 26. Photophysical Properties of Nanosized TiO2 Clusters Included in Zeolites Y, Beta and Mordenite. Chem. Mater. 200113, 715-722.

4) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; Scaiano, J. C. Direct Determination of Single-to-Double Stranded DNA Ratio in Solution Applying Time-resolved Fluorescence Measurements of Dye-DNA Complexes. Chem. Commun. 2000, 689-690.

3) Sortino S.; Cosa, G.; Scaiano, J. C. pH Effect on the Efficiency of the Photodeactivation Pathways of Naphazoline: a Combined Steady State and Time Resolved Study. New J. Chem. 2000, 24, 159-163.

2) Cosa, G.; Martínez, L. J.; Scaiano, J. C. Influence of Solvent Polarity and Base Concentration on the Photochemistry of Ketoprofen: Independent Singlet and Triplet Pathways. Phys. Chem. Chem. Phys. 1999, 1, 3533-3537.

1) Cosa, G.; Chesta, C. A. Estimation of the Bimolecular Rate Constant for Exciplex Formation from the Analysis of its Emission Spectrum. J. Phys. Chem. A. 1997, 101, 4922-4928.

Book Chapters

Book Cover

1) Krumova, K.; Cosa, G.; Overview of Reactive Oxygen Species. In "Singlet Oxygen: Applications in Biosciences and Nanosciences" Nonell, S.; Clors, C.; Royal Society of Chemistry, Cambridge. 2015.

Patents

1) Cosa, G.; Durantini, A. M.; Greene, L. E.; Lincoln, R.; Photodynamic therapy photosensitizers. US Patent App. 15/404,763, 2017.

News and Views

5) Greene, L. E.; Krumova, K.; Godin, R.; Lincoln, R.; Cosa, G.; European Photochemical Association (EPA) Newsletter, Special Report on Fluorogenic Probes. 2014, 60-65.

4) Cosa, G.; Single-molecule fluorescence: Assembling nanoantennas. Nat. Chem. 5, 2013, 159-160.

3) Cosa, G.; PROFILE: Early Excellence in Physical Organic Chemistry. J. Phys. Org. Chem. 25, 2012, 732.

2) Braslavsky, S.; Cosa, G.; Sherman, B.; Thomas, A.; Introduction to the Symposium‐in‐Print: 21st Conference of the Inter‐American Photochemical Society, Mendoza, Argentina, May 2011. Photochem. Photobiol. 88, 2012, 761.

1) Krumova, K.; Cosa, G.; Novel probes for visualizing reactive oxygen species in lipid membranes. Proc. SPIE 7674, 2010, 767406/1-8.