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72) Gidi, Y.; Götte, M.; Cosa, G.; Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method. J. Phys. Chem. B, In Press.

71) Lincoln, R.; Durantini, A. M.; Greene, L. E.; Martínez, S. R.; Knox, R.; Becerra, M. C.; Cosa, G.; meso-Acetoxymethyl BODIPY Dyes for Photodynamic Therapy: Improved Photostability of Singlet Oxygen Photosensitizers. Photochem. Photobiol. Sci., In Press.

Journal Cover

70) Ablenas, C.; Liu, H. W.; Shkriabai, N.; Kvaratskhelia, M.; Cosa, G.; Götte, M.; Dynamic Interconversions of HCV Helicase Binding Modes on its Nucleic Acid Substrate. ACS Infect. Dis., 3, 2017, 99-109.

69) Belzile, M. N.; Godin, R.; Durantini, A. M.; Cosa, G.; Monitoring Chemical and Biological Electron Transfer Reactions with a Fluorogenic Vitamin K Analogue Probe. J. Am. Chem. Soc., 138, 2016, 16388-16397.

68) Calver, C. F.; Schanze, K. S.; Cosa, G.; Biomimetic Light Harvesting Antenna Based on the Self-Assembly of Conjugated Polyelectrolytes Embedded within Lipid Membranes. ACS Nano, 10, 2016, 10598-10605.

67) Glembockyte, V.; Lin, J.; Cosa, G.; Improving the Photostability of Red- and Green-Emissive Single-Molecule Fluorophores via Ni2+ Mediated Excited Triplet-State Quenching. J. Phys. Chem. B, 120, 2016, 11923-11929.

66) Ngure, M.; Issur, M.; Shkriabai, N.; Liu, H. W.; Cosa, G.; Kvaratskhelia, M.; Götte, M.; Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and viral RNA Show Extensive Overlap. ACS Infect. Dis., 2, 2016, 839-851.

65) Greene, L. E.; Godin, R.; Cosa, G.; Fluorogenic Ubiquinone Analogue for Monitoring Chemical and Biological Redox Processes. J. Am. Chem. Soc., 138, 2016, 11327-11334.

64) Godin, R.; Cosa, G.; Counting Single Redox Turnovers: Fluorogenic Antioxidant Conversion and Mass Transport Visualization via Single Molecule Spectroelectrochemistry. J. Phys. Chem. C, 120, 2016, 15349-15353.

63) Durantini, A.; Greene, L. E.; Lincoln, R.; Martinez, S.; Cosa, G.; Reactive Oxygen Species Mediated Activation of a Dormant Singlet Oxygen Photosensitizer: From Autocatalytic Singlet Oxygen Amplification to Chemicontrolled Photodynamic Therapy. J. Am. Chem. Soc., 138, 2016, 1215-1225.

62) Rahbani, J. F.; Hariri, A. A.; Cosa, G.; Sleiman, H. F.; Dynamic DNA Nanotubes: Reversible Switching between Single and Double-Stranded Forms, and Effect of Base Deletions ACS Nano, 9, 2015, 11898-11908.

61) Godin, R.; Sherman, B.; Bergkamp, J.; Chesta, C., A.; Moore, A.; Moore, T; Palacios, R. E.; Cosa, G.; Charge Transfer Dynamics of Fluorescent Dye-Sensitized Electrodes under Applied Biases. J. Phys. Chem. Lett., 6, 2015, 2688-2693.

60) Li, L.; Liu, W.; Zeng, H.; Mu, X.; Cosa, G.; Mi, Z.; Li, C.-J.; Photo-Induced Metal Catalyst Free Aromatic Finkelstein Reaction. J. Am. Chem. Soc., 137, 2015, 8328-8331.

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59) Calver, C. F.; Liu, H.-W.; Cosa, G.; Exploiting Conjugated Polyelectrolyte Photophysics towards Monitoring Real-Time Lipid Membrane-Surface Interaction Dynamics at the Single Particle Level. Langmuir, 31, 2015, 11842-11850.

ACS Editor's Choice

58) Godin, R.; Palacios, R.; Cosa, G.; Heterogeneous Charge Mobility in Individual Conjugated Polyelectrolyte Nanoparticles Revealed by Two-Color Single Particle Spectroelectrochemistry Studies. J. Phys. Chem. C, 119, 2015, 12875-12886.

57) Lincoln, R.; Greene, L.; Bain, C.; Flores-Rizo, J. O.; Bohle, D. S.; Cosa, G.; When Push Comes to Shove: Unravelling the Mechanism and Scope of Non-emissive meso-Unsaturated BODPY dyes. J. Phys. Chem. B, 119, 2015, 4758-4765.

Journal Cover

56) Hariri, A. A.; Hamblin, G.; Gidi, Y.; Sleiman, H. F.; Cosa, G.; Stepwise Growth of Surface-grafted DNA Nanotubes Visualized at the Single Molecule Level. Nature Chem., 7, 2015, 295-300.

55) Glembockyte, V.; Lincoln, R.; Cosa, G.; Cy3 Photoprotection Mediated by Ni2+ for Extended Single-Molecule Imaging: Old Tricks for New Techniques. J. Am. Chem. Soc., 137, 2015, 1116-1122.

54) Godin, R.; Liu, H.-W.; Smith, L.; Cosa, G.; Dye Lipophilicity and Retention in Lipid Membranes: Implications for Single Molecule Spectroscopy. Langmuir, 30, 2014, 11138-11146

53) Karam, P.; Hariri, A.A.; Calver, C.F.; Zhao, X,; Schanze, K.S.; Cosa, G.; Interaction of Anionic Phenylene Ethynylene Polymers with lipids: from membrane embedding to liposome fusion. Langmuir, 30, 2014, 10704-10711.

52) Lincoln, R.; Greene, L. E.; Krumova, K..; Ding, Z.; Cosa, G.; Electronic Excited State Redox Properties for BODIPY Dyes Predicted from Hammett Constants: Estimating the Driving Force of Photoinduced Electron Transfer, J. Phys. Chem. A, 118, 2014, 10622-10630

51) Godin, R.; Liu, H.-W.; Cosa, G. Ambient Condition Oxidation in Individual Liposomes Observed at the Single Molecule Level, Chem. Sci., 5, 2014, 2525-2529.

50) Karam, P.; Powdrill, M. H.; Liu, H.-W.; Vasquez, C.; Mah, W.; Bernatchez, J.; Götte, M.; Cosa, G. Dynamics of HCV RNA-dependent RNA Polymerase NS5B in Complex with RNA, J. Biol. Chem., 289, 2014, 14399-14411.

49) Krumova, K.; Greene, L, E.; Cosa, G. Fluorogenic α-Tocopherol Analogue for Monitoring the Antioxidant Status within the Inner Mitochondrial Membrane of Live Cells, J. Am. Chem. Soc., 135, 2013, 17135-17143.

48) Krumova, K.; Cosa, G.; Fluorogenic Probes for Imaging Reactive Oxygen Species, Photochemistry, 41, 2013, 279-301.

47) Llansola Portoles, M. J.; Bergkamp. J.; Tomlin, J.; Moore, T. A.; Gerdenis, K.; Moore, A. L.; Cosa, G.; Palacios, R. E., Photoinduced Electron Transfer in Perylene TiO2 Nanoassemblies, Photochem. Photobiol., 89, 2013, 1375-1382.

46) Frenette, M.; Cosa, G.; Friščć, T.; Characterization of Organic Solid Forms and Real-time In Situ Monitoring of their Transformations Using Solid-state Fluorescence, Cryst. Eng. Comm., 15, 2013, 5100-5106

45) Hamblin, G.; Hariri, A.; Carneiro, C.; Lau, K. L.; Cosa, G.; Sleiman, H. F.; A Simple Design for DNA Nanotubes from a Minimal Set of Unmodified Strands: Rapid, Room Temperature Assembly and Readily Tunable Structure, ACS Nano, 7, 2013, 3022-3028

44) Marko, R.; Liu, H.-W.; Ablenas, C. J.; Ehteshami, M.; Götte, M.; Cosa; G.; Binding Kinetics and Affinities of Heterodimeric versus Homodimeric HIV-1 Reverse Transcriptase on DNA-DNA Substrates at the Single-Molecule Level, J. Phys. Chem. B, 117, 2013, 4560-4567.

43) Li, B.; Harjani, J. R.; Cormier, N. S.; Madarati, H.;Atkinson, J.; Cosa, G.; Pratt. D. A; Besting Vitamin E: Sidechain Substitution is Key to the Reactivity of Naphthyridinol Antioxidants in Lipid Bilayers, J. Am. Chem. Soc., 135, 2013, 1394-1405.

42) Hernández, L. I.; Godin, R.; Bergkamp, J. J.; Llansola Portolés, M. j.; Sherman, B. D.; Tomlin, J.; Kodis, G.; Méndez-Hernández, D. D.; Bertolotti, S.; Chesta, C. A.; Mariño-Ochoa, E.; Moore, A. L.; Moore, T.; Cosa, G.; Palacios. R. E.; Spectral Characteristics and Photosensitization of TiO2 Nanoparticles in Reverse Micelles by Perylenes, J. Phys. Chem. B, 117, 2013, 4568-4581.

41) Krumova, K.; Sayuri, F.; Cosa, G.; How Lipid Unsaturation, Peroxyl Radical Partitioning and Chromanol lipophilic Tail Affect the Antioxidant Activity of α-Tocopherol: Direct Visualization via High Throughput Fluorescence Studies Conducted with Fluorogenic α-Tocopherol Analogues, J. Am. Chem. Soc., 134, 2012, 10102-10113.

40) Menard, A.; Huang, Y.; Karam, P.; Cosa, G.; Auclair, K.; Site-specific Fluorescent Labelling and Oriented-immobilization of a Triple Mutant of CYP3A4 via C64, Bioconjugate Chem. 23, 2012, 826-836.

39) Liu, H.-W.; Ngo, A. T.; Cosa, G.; Enhancing the Emissive Properties of PPV Conjugated Polyelectrolyte-coated SiO2 Nanoparticles, J. Am. Chem. Soc. 134, 2012, 1648-1652.

38) Borozenko, O.; Godin, R.; Lau, K. L.; Mah, W.; Cosa, G.; Skene, W. G.; Giasson, S., R.;Real-Time Fluorimetric Degrafting Detection of Covalently Attached Fluorescent Polymer Brushes from Silica Substrates- Effects of pH and Salt Concentration, Macromolecules, 44, 2011, 8177-8184.

37) Bergkamp, J. J.; Sherman, B. D.; Mariño-Ochoa, E.; Palacios, R. E.; Cosa, G.; Moore, T. A.; Gust, D.; Moore, A. L.; Synthesis and characterization of octabutoxy silicon phthalocyanines bearing simiconducting metal oxide anchoring groups via a phenoxy linkage, J. P. P. 15, 2011, 1-8.

36) Kostikov, A. P.; Iovkova, L.; Chin, J.; Schirrmacher, E.; Wängler, B.; Wängler, C.; Jurkschat, K.; Cosa, G.; Schirrmacher, R.; N-(4-(di-tert-butyl[18F]fluorosilyl)benzyl)-2-hydroxy-N,N-dimethylethylammonium bromide ([18F]SiFAN+Br-): A novel lead compound for the development of hydrophilic SiFA-based prosthetic groups for 18F-labeling, J. Fluorine Chem. 132, 2011, 27-34.

35) Ngo, A. T.; Karam, P.; Cosa, G.; Conjugated polyelectrolyte-lipid interactions: Opportunities in biosensing (Invited review for the special issue "Perspectives and Challenges for the International Year of Chemistry"), Pure Appl. Chem. 83, 2011, 43-55.

34) Krumova, K.; Cosa, G.; BODIPY Dyes with Tunable Redox Potentials and Functional Groups for Further Tethering: Preparation, Electrochemical and Spectroscopic Characterization, J. Am. Chem. Soc., 132, 2010, 17560-17569.

33) Karam, P.; Ngo, A. T.; Rouiller, I.; Cosa, G.; Unraveling Electronic Energy Transfer in Single Conjugated Polyelectrolytes Encapsulated in Lipid Vesicles, Proc. Nat. Acad. Sci. USA, 107, 2010, 17480-17485.

32) Ngo, A. T.; Lau, K. L.; Quesnel, J. S.; Aboukhalil, R.; Cosa, G.; Deposition of the Anionic Conjugated Polyelectrolyte Poly(phenylenevinylene) onto Silica Nanoparticles via Electrostatic Interactions: Assembly and Single Particle Spectroscopy (special issue in honor of J. C. (Tito) Scaiano), Can. J. Chem.89 2011, 381-384.

31) Solís. C.; Grosso, V.; Faggioli, N.; Cosa, G.; Romero, M.; Previtali, C.; Montejano, H.; Chesta, C. A.; Solvent and Temperature Effects on the Emission Spectra of Excited CT States. A Simple Method for the Experimental Estimation of the Solvent Reorganization Energy, Photochem. Photobiol. Sci. 9, 2010, 675-686.

30) Lo, P.; Karam, P.; Aldaye, F.; Hamblin, G.;, Cosa, G.; Sleiman, H. F.; Loading and Selective Release of Cargo in DNA Nanotubes with Longitudinal Variation, Nature Chem., 2, 2010 , 319-328.

Highlighted in:

29) Ngo, A. T.; Cosa, G.; Assembly of Zwitterionic Phospholipid/Conjugated Polyelectrolyte Complexes: Structure and Photophysical Properties, Langmuir, 26, 2010, 6746-6754.

28) Khatchadourian, A.; Krumova, K.; Boridy, S.; Ngo, A. T.; Maysinger, D.; Cosa, G.; Molecular Imaging of Lipid-Peroxyl Radicals in Living Cells with a Bodipy-α-tocopherol Adduct, Biochemistry, 48, 2009, 5658 - 5668.

27) Krumova, K.; Oleynik, P.; Karam, P.; Cosa, G.; Phenol-based Lipophilic Fluorescent Antioxidant Indicators: a Rational Approach, J. Org. Chem., 74, 2009, 3641 - 3651.

26) Aldaye, F. A.; Lo, P. K.; Karam, P.; McLaughlin, C. K.; Cosa, G.; Sleiman, H. F.; Modular Construction of DNA Nanotubes of Tunable Geometry and Single- or Double-stranded Character, Nature Nanotech., 4, 2009, 349-352.

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25) Cosa, G.; Lukeman, M.; Scaiano, J. C., How Drug Photodegradation Studies Led to the Promise of New Therapies and Some Fundamental Reaction Dynamics along the Way, Acc. Chem. Res., 42, 2009, 599 - 607.

24) Cosa, G.; Scaiano, J. C., Reactivity of Adrenaline toward Alkoxyl Radicals and Carbonyl Triplet States, Org. Biomol. Chem., 6, 2008, 4609 - 4614.

23) Ngo, A. T.; Karam, P.; Fuller, E.; Burger, M; Cosa, G.; Liposome Encapsulation of Conjugated Polyelectrolytes: Toward a Liposome Beacon, J. Am. Chem. Soc., 130, 2008, 457-459.

22) Oleynik, P.; Ishihara, Y.; Cosa, G.; Design and Synthesis of a BODIPY-α-Tocopherol Adduct for Use as an Off/On Fluorescent Antioxidant Indicator, J. Am. Chem. Soc., 129, 2007, 1842-1843.

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21) Cosa, G.; Zeng, Y.; Liu, H.-W.; Landes, C. F.; Makarov, D.; Musier-Forsyth, K.; Barbara, P. F. Evidence for Non-Two-State Kinetics in the Nucleocapsid Protein Chaperoned Opening of DNA Hairpins, J. Phys. Chem. B., 110, 2006, 2419-2426.

20) Liu, H.-W.; Cosa, G.; Landes, C. F.; Zeng, Y.; Kovaleski, B. J.; Mullen, D. G.; Barany, G.; Musier-Forsyth, K.;. Barbara, P. F. Single Molecule FRET Studies of Important Intermediates in the Nucleocapsid Protein Chaperoned Minus-Strand Transfer Step in HIV-1 Reverse transcription, Biophys. J., 89, 2005, 3470-3479.

19) Cosa, G.; Harbron, E. J.; Zeng, Y.; Liu, H.-W.; O'Connor, D. B.; Eta, C.; Musier-Forsyth, K.; Barbara, P. F. Secondary Structure and Secondary Structure Dynamics of DNA Hairpins Complexed with HIV-1 NC Protein, Biophys. J., 87, 2004, 2759-2767.

18) Cosa, G.; Photodegradation and Photosensitization in Pharmaceutical Products: Assessing Drug Phototoxicity, Pure Appl. Chem., 76, 2004, 263-275

17) Llauger, L.; Miranda, M. A.; Cosa, G.; Scaiano, J. C.; Comparative Study of the Reactivities of Different Aroyl-substituted Benzyl Carbanions in Water and DMSO, J. Org. Chem., 69, 2004, 7066-7071.

16) Cosa, G.; Scaiano, J. C. Laser Techniques in the Study of Drug Photochemistry, Photochem. Photobiol., 80, 2004, 159-174.

15) Cosa, G.; Scaiano, J. C. Photochemistry of Diketones: Observation of a Triplet State-oxygen Adduct, J. Am. Chem. Soc., 126, 2004, 8636-8637.

14) Llauger, L.; Cosa, G.; Scaiano, J. C. First Determination of Absolute Rate Constants for the Reaction of Aroyl-substituted Benzyl Carbanions in Water and DMSO, J. Am. Chem. Soc., 124, 2002, 15308-15312.

13) Cosa, G.; Galletero, M. S.; Fernández, L.; Márquez, F.; García, H.; Scaiano, J. C. Tuning the Photocatalytic Activity of Titanium Dioxide by Encapsulation Inside Zeolites Exemplified by the Cases of Thianthrene Photooxygenation and Horseradish Peroxidase Photodeactivation, New J. Chem., 26, 2002, 1448-1455.

12) Cosa, G.; Vinnete, A. L.; McLean, J. R. N.; Scaiano, J. C. Novel DNA Damage Detection Technique Applying Time-resolved Fluorescence Measurements, Anal. Chem., 74, 2002, 6163-6169.

11) Chrétien, M. N.; Cosa, G.; García, H.; Scaiano, J. C. Increasing the Life Expectancy of Carbanions by Zeolite Inclusion, Chem. Commun., 2002, 2154-2155.

10) Boscá, F.; Cosa, G.; Miranda, M. A.; Scaiano, J. C. Inversion of 4-Methoxybenzophenone Triplet in Aqueous Solutions, Photochem. Photobiol. Sci., 1, 2002, 704-709.

9) Cosa, G.; Llauger, L.; Scaiano, J. C.; Miranda, M. A. Absolute Rate Constants for Water Protonation of 1-(3-Benzoylphenyl)alkyl Carbanions, Org. Lett., 4, 2002,, 3083-3085.

8) Cosa, G.; Chrétien, M. N.; Galletero, M. S.; Fornés, V.; García, H.; Scaiano, J. C. Photocatalytic Activity of a Multi-component System Assembled within Zeolites. Case of 2,4,6-Triphenylpyrylium or Ruthenium Trisbipyridyl Photosensitizers and Titanium Dioxide Relays within Zeolite Y, J. Phys. Chem. B., 106, 2002, 2460-2467.

7) Cosa, G.; Purohit, S.; Boscá, F.; Miranda, M. A.; Scaiano, J. C. A Laser Flash Photolysis Study of Fenofibric Acid in Aqueous Buffered Media. Unexpected Triplet State Inversion in a Derivative of 4-alkoxybenzophenone, Photochem. Photobiol., 75, 2002, 193-200.

6) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; McNamee, J. P.; Scaiano, J. C. Photophysical Properties of DNA-stain Dyes Bound to Double and Single Stranded DNA in Aqueous Buffered Solution, Photochem. Photobiol., 73, 2001, 585-599.

5) Corrent S.; Cosa, G.; Scaiano, J. C.; Galletero M. S.; Alvaro, M. A.; Garcia, H. Intrazeolite Photochemistry 26. Photophysical Properties of Nanosized TiO2 Clusters Included in Zeolites Y, Beta and Mordenite, Chem. Mater., 13, 2001, 715-722.

4) Cosa, G.; Focsaneanu K.-S.; McLean, J. R. N.; Scaiano, J. C. Direct Determination of Single-to-Double Stranded DNA Ratio in Solution Applying Time-resolved Fluorescence Measurements of Dye-DNA Complexes, Chem. Commun., 2000, 689-690.

3) Sortino S.; Cosa, G.; Scaiano, J. C. pH Effect on the Efficiency of the Photodeactivation Pathways of Naphazoline: a Combined Steady State and Time Resolved Study, New J. Chem., 24; 2000, 159-163.

2) Cosa, G.; Martínez, L. J.; Scaiano, J. C. Influence of Solvent Polarity and Base Concentration on the Photochemistry of Ketoprofen: Independent Singlet and Triplet Pathways, Phys. Chem. Chem. Phys., 1, 1999, 3533-3537.

1) Cosa, G.; Chesta, C. A. Estimation of the Bimolecular Rate Constant for Exciplex Formation from the Analysis of its Emission Spectrum, J. Phys. Chem. A, 101; 1997, 4922-4928.